Jiann-Shing Shieh, Ph.D. is a Professor of Department of Mechanical Engineering, a joint Professor of Graduate School of Biotechnology and Bioengineering, and also serves as head of department of mechanical engineering of Yuan Ze University in Taiwan. His research interests are focused on biomedical engineering, particularly in bio-signal processing, intelligent analysis and control, medical automation, pain model and control, critical care medicine monitoring and control, dynamic cerebral autoregulation research, and brain death index research. Prof. Shieh’s recent research involved in bio-signal (e.g., ECG, BP, EEG, SPO2, center of pressure (COP) position) analysis, especially in using multi-scale entropy (MSE) and Hilbert-Huang Transform (HHT) in gerontechnology.